What they are collagen biostimulators?
Biostimulants are substances that are injected into the skin, stimulate the natural production of collagen, They provide a rejuvenating effect. Improves sagging skin, texture and radiance progressively and naturally.
When injected, collagen biostimulators trigger an inflammatory reaction in the dermis, activating fibroblasts (cells that produce collagen in the body) and causing the formation of new fibres that provide support to the skin, leaving it firmer, moisturised and radiant.
In which areas can they be applied
biostimulators ?
Biostimulators can be applied to both the face and body. On the face, are used to treat sagging and more advanced signs of ageing, especially in areas such as sagging cheekbones, pronounced nasolabial folds, marionette lines and an ageing neck.
On the body, Biostimulators are often used to increase and remodell the glutes, They also stimulate the body's natural collagen production, improving the volume, projection, firmness, texture and radiance of the skin. For this reason, they are often used to combat cellulite.
In addition to the buttocks, biostimulators can be applied to areas of the body such as knees, abdomen, arms, among others, It provides a rejuvenating effect and significantly improves the skin's firmness, texture and radiance.
TYPES OF BIOSTIMULATORS
The three most common types of collagen biostimulators are Calcium Hydroxyapatite, Polylactic Acid and Polycaprolactone, known commercially as Radiesse, Sculptra and Ellansé, respectively.
• Calcium hydroxyapatite (Radiesse)can provide volume depending on the concentration and number of sessions, similar to the effect of hyaluronic acid.
• Polylactic acid (Sculptra)does not increase the volume, making it ideal for those who want to avoid any increase in volume.
• Polycaprolactone (Ellansé)You can add volume depending on the concentration and number of sessions, similar to Radiesse.
How long the result lasts BIOESTIMULATORS?
The results of collagen biostimulators are gradual and progressive, because they depend on the body's natural response to collagen production.
Normally, at least three sessions are required, with a one-month break between each, to obtain satisfactory results.
The effects of biostimulators can last about 18 months.
Treatment procedure
with collagen biostimulators
This is a simple, quick treatment and the discomfort is minimal and brief. It can be carried out at any time of the year.
To maintain the results, you can have the treatment every 12 to 18 months, as recommended by your doctor.
Skin cleansing and anaesthetic cream
About 15 to 30 minutes before the treatment, the skin is cleansed and an anaesthetic cream is applied (to the most sensitive areas) to reduce discomfort during the treatment.
Bookings
The markings are made in the area where the biostimulants will be applied.
Treatment administration
Biostimulators are administered at strategic points through injections.
Massage
Perform a gentle massage so that the biostimulants are evenly distributed.
Take care after treatment
Treatment with biostimulators is a minimally invasive treatment that involves no recovery time. However, certain precautions must be observed:
- Avoid direct sunlight for 24 hours;
- No sport or physical exertion for 24 hours;
- Avoid saunas, swimming pools and Turkish baths for 24 hours;
- Do not wear make-up for 24 hours.
What results can I expect afterwards of treatment with biostimulators?
The results are gradual and progressive, These results depend on the body's natural response to collagen production. As a rule, they begin to be visible with one session, but it is after 3 sessions that the results are most evident.
Biostimulator injections can then provide the following results:
- Stimulation of collagen production;
- Firmer, tighter skin;
- Improved skin texture and radiance;
- Smoothed lines;
- Rejuvenated appearance.
A Personalised Treatment Plan
To start your treatment with collagen biostimulators, you should have a consultation with one of our aesthetic medicine doctors.
During the first assessment, a medical diagnosis will be made of your skin and a personalised treatment plan will be drawn up to achieve firmer, healthier and more radiant skin.
Medical Specialists
About
Dr Cristina Moreira/ Aesthetic Medicine
DOCTORS' ASSOCIATION: ballot paper no. 52742.
Dr Cristina Moreira has a Master's degree in Medicine from NOVA Medical School since 2011.
He began his medical career in General Surgery and continued his training by specialising in Stomatology and Oro-Maxillary Surgery, where he developed specialised skills in head and neck surgery.
His passion for Aesthetic Medicine was born in parallel with his hospital activity and, since 2019, he has dedicated himself to this area, in which he completed his degree. Master in Regenerative Aesthetic and Anti-Aging Medicine by Faculty of Medicine, Complutense University of Madrid.
In addition to her clinical practice, she maintains a strong link to teaching and scientific research, and is a trainer for Fotona® in workshops on lasers applied to dermatology and aesthetic medicine, as well as a trainer in workshops on injectable medical procedures. She has published more than 30 scientific articles and presented more than 80 scientific papers at national and international congresses.
About
Dr Rita Leite/ Aesthetic Medicine
DOCTORS' ASSOCIATION: ballot paper no. 48069.
Doctor with an Integrated Master's Degree in Medicine from Faculty of Medical Sciences of the New University of Lisbon (FCML), specialising in Radioncology at the Portuguese Institute of Oncology, Francisco Gentil (IPO).
Between 2010-2013 he worked at MD Anderson Cancer Centre (MDACC), in Texas, by the Mayo Clinic in Minnesota and National Cancer Institute (INCA), in Rio de Janeiro.
In 2014 he was a Hospital Assistant at the IPO and since 2015 he has been a hospital assistant at the University Hospital Centre of Central Lisbon (CHULC).
In 2020 she graduated in Aesthetic Medicine from the Portuguese Society of Aesthetic and Cosmetic Medicine (SPMEc).
About
Dr Carolina Medo / Aesthetic Medicine
DOCTORS' ASSOCIATION: card no. 68553, specialising in General and Family Medicine.
Dr Carolina Saldanha Medo completed her Integrated Master's Degree in Medicine at the University of Lisbon. Faculty of Medicine, University of Lisbon in 2019 and the General Practice Internship in 2025.
Her dedication to a global approach to wellbeing led her to the field of Aesthetic Medicine, where she completed postgraduate studies in Aesthetic Medicine at the University of Alcalá, in 2020. She has also completed further training in hormonal balance and longevity.
Dr Carolina believes that true aesthetics is born from balance and that each intervention must respect the individuality and natural harmony of each face.
His practice combines scientific rigour and medical sensitivity, promoting subtle, safe and elegant results, with the aim of enhancing authentic beauty and promoting healthy and conscious ageing.
About
Dr Ana Mendes Gomes / Aesthetic Medicine
DOCTORS' ASSOCIATION: registration no. 55658, specialising in General and Family Medicine.
He completed his Master's Degree in Medicine at Masaryk University Medical School in Brno and graduated in Aesthetic Medicine and Anti-Aging at the Complutense University Madrid.
During his career, he has been trained in minimally invasive procedures, particularly in the application of Toxin, Facial Fillers, Tensor Threads and Facial Mesotherapy, thus differentiating itself in the treatment and prevention of skin ageing.
About
Dr Catarina Guerra / Aesthetic Medicine
DOCTORS' ASSOCIATION: registration no. 55658, specialising in General and Family Medicine.
He built his career in Aesthetic Medicine with solid, international training, having completed specialisations and fellowships in Portugal, Spain, Italy, England and Brazil.
She is a national and international trainer, particularly in the postgraduate programme in Aesthetic Medicine at the University of Alcalá.
About
Dr Joana Alves Barbosa / Dermatologist
DOCTORS' ASSOCIATION: registration no. 64457, specialising in Dermatology.
Master in Medicine from the Institute of Abel Salazar Biomedical Sciences.
He completed his medical training in Dermatovenereology at the Centro Hospitalar e Universitário de Lisboa Central, and complemented his training in Dermatology with internships in Plastic and Reconstructive Surgery at the Centro Hospitalar de Vila Nova de Gaia/Espinho and in Cutaneous Oncology at the IPO do Porto.
His main areas of interest include General, Surgical and Aesthetic Dermatology.
About
Dr Catarina Correia / Dermatologist
DOCTORS' ASSOCIATION: registration no. 63759, specialising in Dermatology.
Dr Catarina Correia completed her Integrated Master's Degree in Medicine at the Faculty of Medicine, University of Porto and completed his Medical Internship in Dermatovenereology at the Centro Hospitalar e Universitário de Lisboa Norte.
He complemented his specific training in Dermatology with internships in Aesthetic Dermatology and LASER, as well as in Trichology (Hair Diseases), at the Dermatology Department of the University of Lisbon. Ramón y Cajal Hospital in Madrid, and in Plastic, Reconstructive and Aesthetic Surgery at the Pedro Hispano Hospital.
Her clinical activity encompasses general dermatology - including acne, rosacea, eczema, screening and assessment of pigmented and non-pigmented skin signs, spots and lesions - hair and nail diseases, dermatological surgery and laser therapy. It is also dedicated to skin rejuvenation procedures, including LASER CO₂, LASER Fotona, microneedling radiofrequency and Ultraformer, among others.
About
Dr Catarina Duarte
DOCTORS' ASSOCIATION: 51027, specialising in otorhinolaryngology.
Master in Medicine from Lisbon Medical School, He then went on to specialise in Otorhinolaryngology at the Santa Maria Hospital in Lisbon, and joined the teaching staff of the Otorhinolaryngology chair as a free assistant. His training in otorhinolaryngology had a strong component in head and neck surgery, but also in rhinology, otology and paediatric laryngology.
About
Dr Filipa Oliveira/ Plastic Surgery
DOCTORS' ASSOCIATION: registration no. 59147, specialising in Reconstructive and Aesthetic Plastic Surgery.
Graduated in Medicine from Faculty of Medicine, University of Porto, where she completed her master's thesis on paediatric scars.
She holds a doctorate in medicine from the University of Münster in Germany.
After completing her speciality, she became a Senior Graduate Assistant (Oberärztin) at the Fachklinik Hornheide and the University of Münster. She is currently collaborating on various research projects at the University of Münster, where she is supervising doctoral students. She is also a regular correspondent for scientific and leisure magazines in Germany.
Frequently Asked Questions about
Collagen biostimulators
Is treatment with biostimulators safe?
Biostimulants are safe substances with a low risk of complications. For the treatment to be carried out safely, we recommend choosing an accredited clinic with a team of professionals experienced in carrying out this type of treatment.
Is it a painful treatment?
This treatment is associated with brief discomfort. It is often performed with an anaesthetic cream to make the experience more comfortable.
When will the results of collagen biostimulators be visible?
The results of the treatment are progressive and gradual, because they depend on the natural production of collagen. As a rule, they begin to be visible with one session, but it is after 3 sessions that the results are most evident.
How long do the results last?
The result of treatment with Biostimulators is superior to that of Hyaluronic Acid, lasting up to 18 months on average.
How many sessions will it take?
As a rule, the treatment is based on a protocol of 3 sessions with an interval of 30 days, which may vary depending on the initial condition of the skin, the desired results and the progression of the results.
What is the price of treatment with collagen biostimulators?
The price of treatment with Biostimulators varies, as it depends on the initial condition of the skin and the number of sessions required. At your first consultation, you will be presented with a treatment plan that is completely tailored to you and the costs involved.
From what age can I have this treatment?
There is no ideal or minimum age. Treatment should be carried out as soon as there are signs of facial sagging.
In what situations is this treatment contraindicated?
Treatment is not recommended for pregnant or breastfeeding women, or for patients with autoimmune diseases. Specific health conditions should be assessed by our medical team.
Does the treatment have any side effects?
The treatment is safe, generally well tolerated and has a low rate of complications. However, swelling, haematomas (bruising), redness and stiffness can occur in the treated area, effects that disappear after a few days.
